Consuming 1 g of omega-3 per day may slow down the rate of biological aging in humans, a post-hoc analysis of DO-HEALTH trial data suggested.
DO-HEALTH tested the effects of three daily interventions, 2,000 IU of vitamin D, 1 g of omega-3, or a strength-training program, on older adults in Europe.
"One of the most critical questions in the field of rejuvenation is whether a treatment exists that can effectively rejuvenate humans, not just mice," reported Heike Bischoff-Ferrari, MD, DrPH, of the University of Zurich.
"Given the well-documented health benefits of omega-3, we explored whether it also influences the most reliable molecular markers of biological age: epigenetic clocks," she told MedPage Today. "Our findings show a robust signal that omega-3 supplementation, algae-based and 1 g per day, rejuvenated biological age by, on average, 3 months in 3 years."
Main findings from the DO-HEALTH clinical trial showed that vitamin D, omega-3, or strength-training interventions did not lead to statistically significant differences in improvement of systolic or diastolic blood pressure, nonvertebral fractures, physical performance, infection rates, or cognitive function in 2,157 older Europeans without major comorbidities. Head over to MedPage Today to read the full story.