More Images
Getting an mRNA COVID-19 shot during the first trimester of pregnancy didn't lead to an increased risk of major structural birth defects, a multi-site retrospective cohort study found.

Major structural birth defects occurred in 1.48% of infants after a first-trimester vaccination and in 1.41% of those without a first-trimester vaccination (adjusted prevalence ratio 1.02, 95% CI 0.78-1.33), Elyse Kharbanda, MD, MPH, of the HealthPartners Institute in Bloomington, Minnesota, and colleagues reported in JAMA Pediatrics.

Additionally, secondary analyses revealed that there were no significant differences between groups when birth defects were grouped by organ system.

"These findings should provide reassurance to pregnant people and their obstetric care practitioners," the authors concluded. Head over to MedPage Today to read more about it.