Tim Largen.
SEATTLE, BOSTON and TOKYO—Aurion Biotech, a clinical-stage biotech company that is developing a platform of advanced therapies to treat ocular diseases, has appointed Tim Largen as vice president of manufacturing. Largen, who is based in Seattle, will lead strategy and development of Aurion Biotech’s global cell manufacturing capabilities. His role will include managing Aurion Biotech’s internal team and as a division of CorneaGen, Inc., working with external teams at Cognate BioServices, Inc., a Charles River Company, and at S-RACMO, a joint venture of Sumitomo Chemical Company, Ltd., and Sumitomo Dainippon Pharma Company, Ltd., to help support cell production in the U.S. and Japan, respectively.

Aurion Biotech’s first candidate is a cell therapy for the treatment of corneal endothelial dysfunction, invented by world-renowned ophthalmic surgeon and research scientist professor Shigeru Kinoshita and his distinguished colleagues at Kyoto Prefecture University of Medicine (KPUM) in Japan. Aurion Biotech’s parent company acquired this technology in 2020; Aurion Biotech is preparing to submit an NDA for market approval in Japan, and an IND for clinical trials in the U.S.

Largen brings to Aurion Biotech over 20 years of experience helping companies move from clinical development into commercial production in gene and cell therapies. He joins Aurion Biotech from Lykan Bioscience, a start-up contract development and manufacturing organization (CDMO) where he led manufacturing sciences and technologies supporting a diverse client base.

Prior to Lykan, Largen spent nearly a decade in roles of increasing responsibility at Dendreon, where he was responsible for establishing and running a high-volume cell therapy production facility. Before Dendreon, Largen held operations and supply chain roles at several life sciences companies, including Argos Therapeutics, Molecular Insight Pharmaceuticals, Inc. (now Progenics), Trace Life Sciences, and NeoRx Corporation.