In today’s practice environment, we have many treatment choices at our disposal, whether they be on-label or off-label. But let’s pause here for a moment because there is more to these distinctions than we might be considering. Everything approved by the Food and Drug Administration (FDA) in the U.S. market has a specified indication for use, making it on-label for a particular purpose. The FDA specifically labels this indication, categorizing something as “on-label” after a rigorous process to ensure safety and efficacy. A physician’s clinical decision to use a medical device or drug off-label for its original indication should be evidence-based and well-thought-out. Read More